% pubman genre = article
@article{item_3022887,
title = {{High-throughput single-cell transcriptomics on organoids}},
author = {Brazovskaja, Agnieska and Treutlein, Barbara and Camp, J. Gray},
language = {eng},
issn = {0958-1669},
doi = {10.1016/j.copbio.2018.11.002},
year = {2019},
date = {2019-02},
abstract = {{Three-dimensional (3D) tissues grown in culture from human stem cells offer the incredible opportunity to analyze and manipulate human development, and to generate patient-specific models of disease. Methods to sequence DNA and RNA in single cells are being used to analyze these so-called {\textquoteleft}organoid{\textquoteright} systems in high-resolution. Single-cell transcriptomics has been used to quantitate the similarity of organoid cells to primary tissue counterparts in the brain, intestine, liver, and kidney, as well as identify cell-specific responses to environmental variables and disease conditions. The merging of these two technologies, single-cell genomics and organoids, will have profound impact on personalized medicine in the near future.}},
journal = {{Current Opinion in Biotechnology}},
volume = {55},
pages = {167--171},
}