%0 Journal Article
%A Riesenberg, Stephan
%A Maricic, Tomislav
%+ The Leipzig School of Human Origins (IMPRS), Max Planck Institute for Evolutionary Anthropology, Max Planck Society
Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society
Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society
%T Targeting repair pathways with small molecules increases precise genome editing in pluripotent stem cells : 
%G eng
%U https://hdl.handle.net/21.11116/0000-0001-6A92-3
%R 10.1038/s41467-018-04609-7
%7 2018-06-04
%D 2018
%8 04.06.2018
%* Review method: peer-reviewed
%X Small molecule inhibitors can influence the choice of repair pathways, enhancing nucleotide substitution and gene integration in CRISPR-mediated genome editing. Here the authors introduce CRISPY, a mix of small molecules that can enhance precise editing with Cpf1 and Cas9D10A in hiPSCs.
%J Nature Communications
%V 9
%] 2164
%I Nature Publishing Group UK
%C London
%@ 2041-1723